ncRNA name | RP11-234O6.2 |
ncRNA Category | lncRNA |
ID | NA |
Ensembl | NA |
Synonyms | NA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | RPE, choroids |
Methods | microarray, qPCR, CCK-8 assay, cell scratch test, flow cytometry |
Expression pattern | down-regulated |
Functional description | By the analyses of the key lncRNAs, it was found that RP11-234O6.2 was downregulated in the aging retinal pigment epithelium (RPE) cellular model. Exogenous RP11-234O6.2 treatment led to increased cell viability and improved apoptosis but it did not affect the cell migration ability of aging RPE cells. |
PubMed ID | 29089757 |
Year | 2017 |
Title | Identification of lncRNAs involved in biological regulation in early age-related macular degeneration. |
Drug-related ncRNA | NO |
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