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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name RP11-234O6.2
ncRNA Category lncRNA
ID NA
Ensembl NA
Synonyms NA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line RPE, choroids
Methods microarray, qPCR, CCK-8 assay, cell scratch test, flow cytometry
Expression pattern down-regulated
Functional description By the analyses of the key lncRNAs, it was found that RP11-234O6.2 was downregulated in the aging retinal pigment epithelium (RPE) cellular model. Exogenous RP11-234O6.2 treatment led to increased cell viability and improved apoptosis but it did not affect the cell migration ability of aging RPE cells.
PubMed ID 29089757
Year 2017
Title Identification of lncRNAs involved in biological regulation in early age-related macular degeneration.
Drug-related ncRNA NO

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